Recombinant Human Lactotransferrin
Catalog #: DC900 Derived From: Human Cells
Recombinant Human Lactotransferrin/LTF is produced by Mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus.
Names(Known as):Lactotransferrin; Lactoferrin; Talalactoferrin; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C; LTF; LF
Mol Mass: 77.3kDa AP Mol Mass: 90kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Reconstituted protein solution should be stored at ≤ -20°C.
Affinity purification chromatography.
Immunogen, calibrator or standard.
Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY