产品Product

其它诊断抗原

Human Lactotransferrin (诊断原料,其它)

Recombinant Human Lactotransferrin


Catalog # DC900        Derived From: Human Cells   


Description:

Recombinant Human Lactotransferrin/LTF is produced by Mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus.

Accession:  P02788

Names(Known as):Lactotransferrin; Lactoferrin; Talalactoferrin; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C; LTF; LF


Quality Control:

Mol Mass:  77.3kDa                   AP Mol Mass:  90kDa, reducing conditions

Purity:  Greater than 95% as determined by reducing SDS-PAGE.


Formulation:

Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.


Shipping:

The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.


Storage:

Reconstituted protein solution should be stored at ≤ -20°C.


Purification: 
Affinity purification chromatography.


Immunoreactivity: 
N.A.


Application:
Immunogen, calibrator or standard.


Background:

Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.


FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY



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