产品Product

生殖

Human FSH (诊断原料,生殖)

Recombinant Human FSH 


Catalog # DCM28        Derived From: Human Cells   


Description:

Recombinant Human Follicle-Stimulating Hormone α/β Dimer is produced by Mammalian expression system and the target gene encoding Ala25-Ser116&Asn19-Glu129 is expressed with a Flag tag&6His at the C-terminus. 

Accession:  P01215&P01225

Names(Known as):Follicle-stimulating hormone; FSH; FSH alpha/beta


Quality Control:

Mol Mass:  10.2&12.5kDa               AP Mol Mass:  20-30kDa, reducing conditions

Purity:  Greater than 95% as determined by reducing SDS-PAGE.


Formulation:

Supplied as a 0.2 μM filtered solution of PBS, pH7.4.


Shipping:

The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.


Storage:

Reconstituted protein solution should be stored at ≤ -20°C.


Purification: 
Affinity purification chromatography.


Immunoreactivity: 
N.A.


Application:
Immunogen, calibrator or standard.


Background:

Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs). FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.


FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY



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